Diabetes can cause the thickening of the walls of small arteries through gradual build up of fat deposits which can eventually clog and harden the walls of blood vessels. These narrowed blood vessels curtail blood circulation to the lower parts of the body which results in wounds on patients’ feet and legs taking an extended period of time to heal. Diabetes can also cause nerve damage that would, in turn, cause patient desensitisation to pain. Peripheral neuropathy could also lead to conditions like diabetic feet and gangrene, leaving surgeons no choice but to amputate.